Axel Methner Selected Research

Glucose (Dextrose)

10/2022	Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels.
1/2020	Bax inhibitor-1 deficiency leads to obesity by increasing Ca2+-dependent insulin secretion.
9/2011	The ancient cell death suppressor BAX inhibitor-1.
1/2003	Short-term serum supplementation improves glucose-oxygen deprivation in primary cortical cultures grown under serum-free conditions.

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Axel Methner Research Topics

Disease

5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 04/2013
4	Multiple Sclerosis 01/2019 - 02/2013
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 04/2014
3	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 06/2004
3	Parkinson Disease (Parkinson's Disease) 01/2020 - 08/2006
3	Huntington Disease (Huntington's Disease) 01/2018 - 01/2013
3	Neoplasms (Cancer) 01/2018 - 09/2011
2	Polyneuropathies (Polyneuropathy) 01/2022 - 10/2019
2	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 10/2019 - 01/2012
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019 - 12/2017
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2019 - 01/2017
2	Inflammation (Inflammations) 10/2018 - 04/2016
2	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2017 - 08/2014
2	Ganglion Cysts (Ganglion) 07/2017 - 01/2012
2	Nervous System Heredodegenerative Disorders 02/2017 - 01/2013
2	Relapsing-Remitting Multiple Sclerosis 01/2017 - 07/2012
2	Breast Neoplasms (Breast Cancer) 07/2016 - 01/2011
2	Ischemia 08/2014 - 01/2005
2	Epilepsy (Aura) 06/2014 - 12/2011
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2014 - 10/2009
1	Hyperglycemia 10/2022
1	Muscular Diseases (Myopathy) 10/2022
1	Obesity 01/2020
1	Insulin Resistance 01/2020
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Coronary Artery Disease (Coronary Atherosclerosis) 10/2018
1	Body Weight (Weight, Body) 12/2017
1	Atrophy 07/2017
1	Papilledema 07/2017
1	Pseudotumor Cerebri (Idiopathic Intracranial Hypertension) 07/2017
1	Demyelinating Diseases (Demyelinating Disease) 01/2017
1	Disease Progression 01/2017
1	Hepatocellular Carcinoma (Hepatoma) 07/2016
1	Restless Legs Syndrome (Restless Legs) 07/2016
1	Optic Neuritis (Retrobulbar Neuritis) 04/2016
1	Retinal Degeneration 04/2016
1	Infarction (Infarctions) 08/2015
1	Retinal Artery Occlusion 08/2015
1	Pelizaeus-Merzbacher Disease 08/2015
1	Gliosis 08/2015
1	Stroke (Strokes) 08/2014
1	Heart Arrest (Cardiac Arrest) 08/2014
1	Glioblastoma (Glioblastoma Multiforme) 06/2014
1	Neurocognitive Disorders (Clerambault Syndrome) 12/2013
1	Abscess 11/2012
1	Parkinsonian Disorders (Parkinsonism) 01/2012
1	Type 4A Charcot-Marie-Tooth disease 01/2012
1	Hepatolenticular Degeneration (Wilson's Disease) 01/2012
1	Fibrosis (Cirrhosis) 01/2012
1	Temporal Lobe Epilepsy 12/2011

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2011
8	Glutathione (Reduced Glutathione)IBA 01/2019 - 08/2006
6	CalciumIBA 10/2022 - 12/2011
6	Retinaldehyde (Retinal)IBA 07/2017 - 01/2012
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 09/2011
4	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 01/2003
4	Dimethyl FumarateIBA 01/2019 - 07/2012
4	Glutamic Acid (Glutamate)FDA Link 01/2018 - 10/2009
2	Messenger RNA (mRNA)IBA 01/2024 - 10/2018
2	Biomarkers (Surrogate Marker)IBA 10/2018 - 04/2016
2	polyglutamineIBA 02/2017 - 01/2013
2	Oxygen (Dioxygen)IBA 08/2014 - 01/2003
2	AntiportersIBA 06/2014 - 04/2013
2	Cystine (L-Cystine)IBA 06/2014 - 04/2013
1	Adenosine (Adenocard)FDA LinkGeneric 01/2024
1	Amyloid (Amyloid Fibrils)IBA 01/2024
1	Mitochondrial Permeability Transition PoreIBA 10/2022
1	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2022
1	GDAP proteinIBA 01/2022
1	Probucol (Lorelco)FDA Link 08/2020
1	IsotopesIBA 01/2020
1	GTP Phosphohydrolases (GTPases)IBA 10/2019
1	Adenosine Triphosphate (ATP)IBA 10/2019
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 10/2018
1	PresenilinsIBA 06/2018
1	Presenilin-1IBA 06/2018
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2018
1	Homer Scaffolding Proteins (Homer 1)IBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	AntioxidantsIBA 01/2018
1	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA 01/2018
1	IronIBA 01/2018
1	Metformin (Glucophage)FDA LinkGeneric 01/2018
1	NAD (NADH)IBA 01/2018
1	AndrogensIBA 07/2016
1	Transcription Factors (Transcription Factor)IBA 07/2016
1	CurcuminIBA 08/2015
1	Peptide Initiation Factors (Initiation Factor)IBA 06/2014
1	Activating Transcription Factor 4IBA 06/2014
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2014
1	Cysteine (L-Cysteine)FDA Link 06/2014
1	Phosphatidylinositols (Phosphatidylinositol)IBA 06/2014
1	env Gene ProductsIBA 12/2013
1	Potassium Channels (Potassium Channel)IBA 02/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2012
1	CopperIBA 01/2012
1	NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA 09/2011

Therapy/Procedure

6	Therapeutics 01/2018 - 08/2006
1	Oral Administration 12/2017
1	Lasers (Laser) 08/2015